Abstract
Biclustering, which is simultaneous clustering of columns and rows in data matrix, became an issue when classical clustering algorithms proved not to be good enough to detect similar expressions of genes under subset of conditions. Biclustering algorithms may be also applied to different datasets, such as medical, economical, social networks etc. In this article we explain the concept beneath hybrid biclustering algorithms and present details of propagation-based biclustering, a novel approach for extracting inclusion-maximal gene expression motifs conserved in gene microarray data. We prove that this approach may successfully compete with other well-recognized biclustering algorithms.
Keywords
- Biclustering
- bioinformatics
- pattern matching
- data mining
- microarray gene expression data
- conserved gene expression motifs
Cite this article
@article{cai-1804,
author = {Patryk Orzechowski and Krzysztof Boryczko},
title = {Propagation-Based Biclustering Algorithm for Extracting Inclusion-Maximal Motifs},
journal = {Computing and Informatics},
volume = {35},
number = {2},
pages = {391--410},
year = {2016},
issn = {1335-9150},
url = {https://cai.type.sk/content/2016/2/propagation-based-biclustering-algorithm-for-extracting-inclusion-maximal-motifs/}
}
TY - JOUR AU - Patryk Orzechowski AU - Krzysztof Boryczko TI - Propagation-Based Biclustering Algorithm for Extracting Inclusion-Maximal Motifs JO - Computing and Informatics VL - 35 IS - 2 SP - 391 EP - 410 PY - 2016 SN - 1335-9150 UR - https://cai.type.sk/content/2016/2/propagation-based-biclustering-algorithm-for-extracting-inclusion-maximal-motifs/ KW - Biclustering KW - bioinformatics KW - pattern matching KW - data mining KW - microarray gene expression data KW - conserved gene expression motifs ER -
Orzechowski, P., & Boryczko, K. (2016). Propagation-Based Biclustering Algorithm for Extracting Inclusion-Maximal Motifs. Computing and Informatics, 35(2), 391–410. https://cai.type.sk/content/2016/2/propagation-based-biclustering-algorithm-for-extracting-inclusion-maximal-motifs/